Concerns over data in key dabigatran trial

Concerns over data in key dabigatran trial.

One of the key selling points of the new oral anticoagulant dabigatran for use in stroke prevention in non-valvular atrial fibrillation is that the drug requires no time consuming anticoagulant activity or drug plasma level monitoring. But the evidence on which these claims were based has been called into question by the publication of new material as a result of an investigation in The BMJ. Do...

Separating Key Concerns in Query Processing

Declarative query languages are the most convenient and most productive abstraction for interacting with complex data management systems. While the developer can focus on the application logic, the compiler takes care of translating and optimizing a query for efficient execution. Today, applications increasingly call for declarative data management for many novel storage designs and system arch...

Private Key based query on encrypted data

Nowadays, users of information systems have inclination to use a central server to decrease data transferring and maintenance costs. Since such a system is not so trustworthy, users' data usually upkeeps encrypted. However, encryption is not a nostrum for security problems and cannot guarantee the data security. In other words, there are some techniques that can endanger security of encrypted d...

Key Issues & Concerns of Adolescent Students

The importance of postapproval data for dabigatran.

Dabigatran was approved by the Food and Drug Administration (FDA) in 2010via theacceleratedpathwayafter a6-month review. The haste to approve novel drugs places an increasing importance on postapproval data to help better understand risks and benefits. Thus, the postapproval data on the use of dabigatran in the Medicare population are informative in alerting us to risks associated with real-wor...